The 2025 NFL divisional round is set to deliver four thrilling playoff matchups this weekend. On Saturday, Josh Allen and the Bills will travel to Denver to take on the Broncos, followed by an NFC West battle between the 49ers and Seahawks in Seattle. Sunday features the Texans aiming for their first-ever divisional round victory against the Patriots, while Matthew Stafford and the Rams visit Caleb Williams in Chicago.
Our NFL Nation reporters bring you insider information from the locker room, highlighting key storylines and observations. Analytics expert Seth Walder shares essential stats for each game, while analyst Ben Solak offers bold predictions. Additionally, Matt Bowen identifies a crucial matchup X factor to watch, and betting analyst Pamela Maldonado suggests intriguing bets for each contest. Finally, staff writer Kevin Seifert provides insights on officiating crews, and our Football Power Index (FPI) projects game outcomes.
Matchup Breakdown: Bills vs. Broncos
The Bills are on the brink of making their second consecutive appearance in the AFC Championship Game and the third in Josh Allen“s career. However, challenges loom as the team deals with multiple wide receiver injuries, including Tyrell Shavers, Gabe Davis, and Joshua Palmer. Allen himself is nursing injuries to his right foot, left knee, and right finger but fully participated in practice earlier this week. Protecting him will be crucial against a formidable Broncos defense that recorded 68 sacks this season, ranking among the best historically.
For the Broncos, facing Allen brings a wave of nostalgia for fans, as he was once a coveted prospect in the 2018 draft. The Bills eliminated Denver from the playoffs last year with a decisive 31-7 victory. This time, the Bills will rely on the league”s top rushing attack, led by James Cook III, who amassed 1,621 rushing yards this season.
Statistically, the Bills struggle against the run, ranking 31st in EPA allowed per designed run. The Broncos, however, have not maximized their run game, posting a negative EPA per designed run. This matchup raises questions about whether Denver can exploit Buffalo”s defensive weaknesses.
Key Predictions and Betting Insights
Analyst Ben Solak predicts that Broncos running back RJ Harvey will achieve his first 100-yard game as the team focuses on controlling the clock. Meanwhile, Brandin Cooks of the Bills is highlighted as a significant X factor with his potential for big plays against Denver”s defense.
In terms of betting, Pamela Maldonado suggests taking the under on total points, forecasting a game with limited scoring opportunities due to both teams” tendencies in the red zone. Officiating might also play a role, as the Broncos led the league in defensive pass interference penalties this season.
Matchup Breakdown: 49ers vs. Seahawks
The 49ers and Seahawks are set for a rematch after their last meeting just weeks ago. Kyle Shanahan aims to avoid overthinking the previous loss, while Seattle“s defense, which excelled in limiting the 49ers to just a field goal last time, looks to replicate that performance.
Despite Christian McCaffrey struggling this season, the Seahawks will need to maintain their strong run defense to stifle San Francisco”s offensive efforts. Betting odds favor Seattle, who are expected to control the game”s pace.
Texans vs. Patriots & Rams vs. Bears Preview
The Texans are looking to break their winless streak in the divisional round, with C.J. Stroud eager to prove himself against a tough Patriots defense. Mike Vrabel acknowledges the challenge posed by Houston”s defensive unit.
Finally, the Rams take on the Bears in frigid Chicago, where Matthew Stafford faces the challenge of playing in the cold for the first time. The Bears hope to reignite their running game, which has struggled recently.
This playoff weekend promises excitement and drama as teams vie for a spot in the conference championships. Stay tuned for all the action.
