The Buffalo Bills and Denver Broncos will face off this Saturday at Mile High in an AFC Divisional playoff game that promises to showcase postseason toughness against a newly minted No. 1 seed. The Broncos, boasting a record of 14-3, utilized their bye week to recuperate, while the Bills, who stand at 13-5, are coming off a hard-fought Wild Card victory that came with significant injuries.
Buffalo”s recent triumph was bittersweet, as they suffered critical injuries to their wide receiver corps, including multiple season-ending ACL tears. This leaves the NFL”s top-ranked rushing attack in a precarious position as they prepare for a quick turnaround. Quarterback Josh Allen, the reigning MVP, is set to play despite dealing with several injuries to his foot, knee, and finger. However, he will have to tackle a formidable Denver secondary without the help of veteran safety Jordan Poyer.
The Broncos enter the game as slight favorites, with a spread of 1.5 points, looking to capitalize on a pass rush that led the league in sacks this season. This matchup presents a classic “rest versus rust” scenario, where Denver”s fresh legs will test Buffalo”s depth and resilience.
Game Details and Betting Preview
The game is scheduled for Saturday, January 17, 2026, with kickoff set for 4:30 PM EST at Empower Field at Mile High. Current betting lines show the Bills at +1.5 (-112) and the Broncos at -1.5 (-105), while the moneyline is at Bills +100 and Broncos -115. The over/under is set at 45.5, reflecting a balanced expectation for scoring.
According to simulations run by Dimers.com, the Broncos have a 56% chance to win this matchup, reflecting their strong performance metrics. The predictions indicate that both teams have an equal 50% chance of covering the spread, with the total points also seen as a 50-50 proposition.
Expert Predictions and Player Props
Dimers” expert analysis suggests that the best bet for this game is to take the Broncos on the moneyline at -115. Their projections estimate a final score of 23-21 in favor of Denver based on an extensive data-driven model.
In terms of player props, James Cook is predicted to have the highest chance of scoring the first touchdown for Buffalo at 10.5%, with Josh Allen close behind at 9.6%. For Denver, RJ Harvey leads with a 12.7% chance to score first. Overall, both teams present intriguing options for anytime touchdown bets, particularly for their leading offensive players.
This upcoming game is set to provide a thrilling atmosphere as the Bills and Broncos vie for a spot in the next round of the playoffs. Fans and bettors alike will be watching closely as these two teams showcase their strategies and strengths on Saturday.
